This website has been developed by ALK and is intended for healthcare professionals only. Jext® is indicated in the emergency treatment of severe acute allergic reactions (anaphylaxis) to insect stings or bites, foods, drugs and other allergens as well as idiopathic or exercise induced anaphylaxis. Prescribing Information UK ROI

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Jext® is vital for your patients who suffer from the risks of anaphylaxis1

Jext® comes in two different doses1,2

15-30kg

150 micrograms if you weigh between 15-30kg

>30kg

300 micrograms if you weigh over 30kg

Adrenaline

The prompt use of intramuscular adrenaline as first-line management is recommended with the availability of adrenaline auto-injectors to patients in the community.3

Anaphylaxis emergency management

Use intramuscular adrenaline in the mid-thigh quickly as first-line management.3

  • Prescribe autoinjectors for people at risk to use in the community.
  • Use simulation training and visual prompts to improve healthcare professionals’ knowledge of anaphylaxis.
  • Seek out and review pharmacokinetic data for each adrenaline autoinjector because products are not interchangeable.

In addition to the early use of adrenaline3

The trigger should be removed where possible, posture should be optimized, and assistance should be sought from emergency medical services in the community or the emergency team in hospital.
  • To ensure adequate venous return, patients experiencing anaphylaxis should lie flat with their legs raised.
  • Where respiratory distress is the predominant presentation, patients may prefer to sit up with elevated legs.
  • If pregnant, they can be placed on their left side with the bed in a head-down position.
  • Where unconscious, patients can be placed in the recovery position.
  • Avoid any abrupt change to a more upright posture.

How to use Jext®1

Step 1

Grasp the Jext® in your dominant hand (the one you use to write with) with your thumb closest to the yellow cap.

Step 2
Pull off the yellow cap with your other hand.
Step 3
Place the black injector tip against your outer thigh, holding the injector at a right angle (approx. 90°) to the thigh.
Step 4
Push the black tip firmly into your outer thigh until you hear a ‘click’ confirming the injection has started, then keep it pushed in. Hold the injector firmly in place against the thigh for 10 seconds (a slow count to 10) then remove. The black tip will extend automatically and hide the needle.
Step 5
Massage the injection area for 10 seconds. Seek immediate medical help.

You should explain to your patients when and how to use their Jext®. If they begin to experience the symptoms of anaphylaxis it is important that they use it immediately1,2

If symptoms don’t improve or if deterioration occurs, a second Jext® may be used 5-15 minutes after the first injection1,2

For more information, please refer to section 4.2 of the Summary of Product Characteristics for instructions to be conveyed to the patient/carer regarding actions to be taken following each use of Jext®

Video demonstration

Watch the demonstration video to familiarise yourself, family and friends with what to do in the event of an anaphylactic reaction, how to recognise the symptoms, and how to administer Jext®.

*Educational Risk Minimisation Materials to help reduce the risk associated with using this medicine.
References

1. EMC. 2023. Jext® 300micrograms solution for injection in pre-filled pen Summary of Product Characteristics
2. EMC. 2023 Jext®150micrograms solution for injection in pre-filled pen Summary of Product Characteristics
3. Muraro A et al. 2022. EAACI guideline: Anaphylaxis (2021 update). Allergy. 77(2):357-377

January 2025

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